Endocrine Abstracts

The uterus is an androgen-responsive organ; androgen receptors (AR) are expressed in human endometrial stromal fibroblasts and can regulate proliferation and survival of this cell type. Although chronic androgen exposure results in atrophy of human endometrium, previous studies have suggested that it may have trophic effects in the rodent uterus. We hypothesised that androgens may have different impacts on endometrial function in the presence or absence of oestrogens. In the c...